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Alpha Brain Review

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The best way to test a nootropic is to mute the marketing, study the ingredients, look at the dosages, and report the effects. That’s exactly what we’ve done here in this in-depth Alpha Brain review. Here’s what we found.

In this Alpha Brain review, we’re putting Onnit’s nootropic to the test. Onnit Labs isn’t new to the health supplement scene, and led by their flagship nootropic, they’re now offering a range of Alpha Brain variations.

My goal? To see if these claims actually hold up. I’ll be trying the original Alpha Brain version for myself and looking closely at what’s in it.

Packed with a blend of vitamins, plant extracts, and other compounds such as Vitamin B6, Cat’s Claw, and L-Tyrosine, Alpha Brain claims to optimize brain function. But it’s not just about the ingredients. It’s about how they work together, their doses, and their effects on our brain health.

So, are you ready to explore the truth behind Alpha Brain? Let’s cut through the marketing noise and get down to the science of this popular nootropic blend.

Quick Verdict: Alpha Brain

Alpha Brain bottle

Alpha Brain is, I’d say, a mid-tier nootropic. It does bring results, with the use of its three blends.

I did note an uptick in my memory, energy levels and concentration, some welcome improvements both professionally and personally.

My biggest issue with Alpha Brain is its lack of transparency when it comes to dosages. We can’t know for sure just how much we are getting, of which ingredient, in each blend. This obscures crucial details, limiting our ability to accurately evaluate its efficacy and safety profile.

That being said, its all-natural formula is generally considered safe, and will help cognitively – perhaps just not quite as much as some others, like NooCube and Hunter Focus, which offer more comprehensive and transparent formulas.

What Is Alpha Brain?

If your goal is to boost your cognitive prowess, learning speed, or simply maintain an active mind, Alpha Brain could be an excellent choice – at least, that’s what’s broadcast by manufacturer Onnit and ex-Fear Factor host Joe Rogan, who often loudly promotes Alpha Brain’s nootropic benefits (and also has shares in it).

Alpha Brain in hand

Alpha Brain’s formula is a collection of three separate blends, each designed with a specific purpose:

  • The Onnit Flow Blend has been created to enhance brain flow, often associated with improved focus and concentration.
  • A robust Onnit Focus Blend fosters an effective concoction that aims to enhance mental clarity and augment the capacity of one’s memory.
  • Then there’s the Onnit Fuel Blend, which is designed to re-fuel your brain, giving it the energy required to function at full capacity.

Flow, Focus, and Fuel – three key aspects for optimal cognitive ability.

Alpha Brain could also be a great option for anyone who’s sensitive to caffeine or simply want to avoid it, as it doesn’t contain any. Me personally? I like a sprinkle of caffeine, it works well for me. So I was keen to find out how Alpha Brain performed without it (find out in a moment).

Another key point is that Onnit offer a ‘KeepIt™’ Money-Back Guarantee on their 30-capsule bottles. It’s not the most generous guarantee I’ve seen, but a great way to trial it with peace of mind, and many supplements don’t offer it at all.

Alpha Brain Benefits

In the area of neuroscience, Alpha brainwaves are highly coveted. They are associated with a relaxed yet focused state of mind.

Think of it as the sweet spot between being alert and being not overly stressed. It’s the zone that artists, athletes, and high-performing individuals often report being in when they’re at the peak of their game.

Alpha Brain Bottle

Alpha Brain promotes the production of these brainwaves, helping users tap into this state of enhanced focus and mental clarity. It optimizes the levels of Acetylcholine we have, which is a neurotransmitter crucial for memory, attention, and cognitive processing.

So how can this help us in real terms? Alpha Brain claims to help us in the following ways:

Improvement In Memory

Memory loss isn’t just an age-related issue. Even younger adults can experience lapses. Be it short term or long term, memory is a cognitive function we desperately rely on.

Alpha Brain promises to assist in this regard. By enhancing neurotransmitter function and optimizing brainwave patterns, it lends a helping hand to your ability to memorize and recall information.

Executive Function Support

In the working world, executive functions are king. They’re the set of skills that allow you to manage time, pay attention, switch focus, plan and organize, remember details, and multitask.

Increased Focus

Being able to zero in on a task without the incessant chatter of distractions dampening your progress is something we all want. Increased focus can transform a workday from manic to productive. Alpha Brain, through its blend of nootropic ingredients, strives to provide this benefit.


It’s not just about enhancing function, it’s also about preserving brain function over time. The term neuroprotection refers to the mechanisms and strategies used to protect the brain against damage and degeneration. Alpha Brain says it has this covered too, promoting overall brain health and acting as a cognitive investment for the future.

Throughout this review, remember, it’s always important to merge the use of such supplements with a balanced lifestyle, and consult a healthcare professional before you begin. With that being said, let’s look at what is in Alpha Brain.

Alpha Brain Ingredients

The benefits we’ve discussed can only be delivered with a quality formula. I’ve tested some incredible nootropics in the past, often with similar ingredients dosed generously, plus a little extra something.

Dosage is indeed an important aspect when studying a formula – and this is where Alpha Brain lose a wall of points. They give us only proprietary blends, which basically means they don’t fully disclose how much of each ingredient is in there – only the total collectively.

Alpha Brain ingredients

This aggravates me. I see no reason why I supplement these days finds it necessary to hold any information back from us consumers. We like facts, and we like transparency.

However, I shall work with what they give us, and go from there. We’ve got three different blends that focus on various cognitive aspects, so let’s take a look at each.

Onnit Flow Blend – 650mg

According to Alpha Brain, the objective of this Flow blend is to promote alpha brainwave production. Here’s what’s in it:


L-tyrosine is noteworthy for enhancing cognitive adaptability, aiding in the seamless transition between different tasks. It is particularly valuable in high-pressure situations, or when managing multiple tasks simultaneously.

Studies suggest consuming at least 2 grams of L-Tyrosine can significantly improve overall mental performance. Unfortunately, we don’t know quite how much of it is in the blend.


Theanine is lauded for its soothing effects. It reduces stress and refines focus, serving as the calm amidst a storm of cognitive activity.

Research highlights its effectiveness in reducing stress and anxiety, and is unique in its ability to induce relaxation without causing drowsiness, making it a vital element in supporting mental wellbeing, particularly in stressful situations.

Oat Straw Extract

This element is more of a wild card in the mix. Research suggests that 800mg of oat straw extract may improve task performance speed, memory recall, and executive functioning.

However, these initial results call for further, more comprehensive studies to establish oat straw’s consistent cognitive benefits reliably, and we don’t know how much we have here.


A key player in cognitive functions, Phosphatidylserine is confirmed to contribute actively to brain health, particularly among the elderly.

A daily intake ranging from 100-300 mg of phosphatidylserine has been shown to positively impact memory in older adults experiencing cognitive decline. Additionally, it holds potential benefits for individuals dealing with neurodegenerative and neurodevelopmental conditions.

Onnit Focus Blend – 240mg

Shifting gears to the Onnit Focus Blend, this blend aims to support the maintenance of optimal acetylcholine levels, a neurotransmitter crucial for various brain functions, including memory.


The benefits of Alpha-GPC are intriguing yet lack an extensive scientific foundation. Nonetheless, some users vouch for its cognitive perks.

Alpha GPC shows promise in enhancing cognitive functions, outperforming caffeine in tasks that take a high level of concentration.

Bacopa Monnieri

Bacopa Monnieri is a heavy hitter in this blend, well known for its ability to improve cognition. Research indicates that consuming 300 mg daily greatly enhances memory acquisition and retention, especially for older people.

It’s effective with memory retention, memory recall, attention speed, and cognitive performance, bearing a heavy load of nootropic effects on its broad shoulders.

Toothed Clubmoss – Huperzine A

For athletes in high-impact sports, Huperzine-A might be beneficial, with a suggested dose of 1mg/kg of body weight daily to potentially assist in recovering from traumatic brain injuries.

It also may possibly help with enhancing brain function and assisting Alzheimer’s disease patients.

However, the immediate cognitive and physical benefits of Huperzine-A are not yet confirmed, requiring more research for validation.

Onnit Fuel Blend – 60mg

Onnit Fuel Blend has been created by Alpha Brain to promote brain health, contributing to optimal neural communication.


L-Leucine is an essential amino acid aimed at supporting your overall bodily health.

The only paper I could find regarding L-leucine and its cognitive protective effects was a rat study suggesting leucine drops in the brain’s spinal fluid when newborn rats are separated from their parents and could damage neurons, resulting in cognitive impairment.

It would be great to see some more human-based research on this.


Pterostilbene is a powerful antioxidant that serves to battle oxidative stress in your body, and may combat cognitive decline in relation to aging.

Cat’s Claw

For some reason, Cats Claw isn’t added to a specific blend but is a standalone ingredient on the label.

Although cat’s claw is frequently included in nootropic blends due to its history in helping treat a large number of ailments, including Alzheimer’s disease, arthritis and even some cancers, no published study has been done to verify the nootropic’s efficacy.

Vitamin B6, 10mg

All B vitamins are important for nerve and brain health (so it would’ve been nice to see some more here), but vitamin B6, also known as pyridoxine, is one of the most critical in this arena.

This essential vitamin helps our brain create neurotransmitters, amino acids, and proteins, regulate energy use in the brain, and maintain proper brain and immune system development and functioning.

Being deficient in it has been linked to a number of concerns, including cognitive impairment, anxiety, migraines, depression, and even seizures. We don’t make vitamin B6 naturally, so this added supplementation will be very advantageous.

My Experience

After hearing positive feedback and assurances of significant memory and focus enhancement, I decided to give Alpha Brain a try. My experience, as it turned out, was mixed.

The recommended dose for Alpha Brain is 2 capsules per day, with a light meal. A great start, as it’s convenient and easy – some nootropics require 4 or even 6 capsules a day.

The first week of taking Alpha Brain really put its ‘Onnit Flow Blend’ to the test. This blend is designed to help you get “in the zone” and tuned into your task. Personally, I noticed an apparent enhancement in my focus. Tasks that typically resulted in mental fatigue felt easier to navigate.

holding Alpha Brain capsules

The increase in my cognitive stamina was thanks, I believe, to the ‘Onnit Fuel Blend’, including L-Leucine and Pterostilbene. Even at the end of the day, I felt alert and engaged, able to carry out my activities with the same mental vigor as in the morning. This is a huge asset for anyone dealing with intense workdays.

In week three, I began to notice an uptick in my memory recall, particularly verbal. It reminded me of the study’s findings, where researchers observed pronounced improvement in delayed verbal recall among Alpha Brain users. As someone who gives presentations frequently, this was a welcome improvement.

Finally, I want to talk about the ‘Onnit Focus Blend.’ After six weeks, I felt a distinct change in my ability to concentrate. The blend, which consists of Alpha GPC, Bacopa (leaves) Extract, and Toothed Clubmoss, seemed to help keep my thinking razor-sharp.

Overall, I must say I felt more productive and mentally agile while using Alpha Brain. Not overwhelmingly, but definitely noticeable.

Of course, results may vary across individuals and should be used responsibly. Always consult with a healthcare professional before beginning any supplement regimen. But for me personally, the results were great.

My only real gripe is not knowing just how much of each ingredient I’m taking. Personally, I also prefer a stimulant, and get good results from the likes of Hunter Focus, which contains an extra helpful kick of caffeine (and others). But that’s just me.

Overall Verdict

After a comprehensive review, it’s clear that Alpha Brain holds its place in the cognitive enhancer market. Its unique blend of nootropics, focus on Acetylcholine, and brainwave production enhancement are noteworthy features.

The use of proprietary blends and the lack of transparency in ingredient dosages, however, are significant drawbacks for me.

My personal experience with Alpha Brain showed a modest boost in cognitive function. Perhaps not quite as much as I would enjoy with other nootropics (NooCube is an excellent one, also with no caffeine), but it did work. It did have an impact.

I’d say there’s work to do in terms of dosages, transparency, and perhaps adding a few proven helpful ingredients to get more for your money. But Alpha Brain still offers positive results in improving cognitive ability.